Maternal Clofibrate Administration Amplifies Fetal Peroxisomes

Maternal administration of flecainide to terminate and suppress fetal tachycardia.

Fetal echocardiography has allowed fetal arrhythmias to be identified and accurately diagnosed. Because a fetal tachycardia is often detected before an elective delivery is safe considerable interest has focused on treatment by giving drugs to the mother. Digoxin is accepted as the drug of first choice, but no consensus exists on second line drugs.' 2 We present the first report of giving fleca...

Maternal-fetal intervention and fetal care centers.

The past 2 decades have yielded profound advances in the fields of prenatal diagnosis and fetal intervention. Although fetal interventions are driven by a beneficence-based motivation to improve fetal and neonatal outcomes, advancement in fetal therapies raises ethical issues surrounding maternal autonomy and decision-making, concepts of innovation versus research, and organizational aspects wi...

Maternal-Fetal Thyroid Interactions

Tobramycin: maternal-fetal pharmacology.

To investigate the maternal-fetal transfer of tobramycin (TBM) and its distribution in the fetus, a single dose of 2 mg/kg was administered intramuscularly to 35 pregnant patients (13 first trimester, 22 second trimester) 0.5 to 34 h before hysterectomy. TBM concentration was assayed microbiologically in maternal serum, fetal tissues (placenta, brain, lung, liver, and kidney), and fluids (amnio...

Fetal-maternal interface

The existence of allogeneic cells within an individual has been demonstrated in multiple fields such as hematopoietic stem cell or solid organ transplantation, non-depleted blood transfusions and the most common form which is bidirectional maternal-fetal cell trafficking, whereby cells from the fetus pass through the placental barrier. In order to graphically illustrate this early natural pheno...